Can samples degrade?

Yes. Improper temperature, delayed processing, or shipping delays can compromise sample integrity. Experienced providers mitigate these risks through proper handling and shipping selection.

Degradation risks include hemolysis from improper collection technique, analyte breakdown from temperature excursions, and clotting in anticoagulated tubes if mixing steps are skipped. Each tube type has specific handling requirements that trained phlebotomists follow on every draw.